The Maine Medical Center Research Institute (MMCRI) BioBank is available for researchers to obtain tissue and tissue-related services by the formal submission and approval of an sample request. Banking tissue involves the allocation of small pieces of the specimen, both abnormal and normal, if attainable, and the creation of a number of vials containing a weighed quantity of tissue to be snap frozen. Portions of the sample contiguous with each frozen section are then placed in cassettes to be embedded in paraffin. We also provide a range of other tissue preservation methods. Below are some descriptions to better define each banking method.