Susan Miesfeldt

Medical Oncologist

Director, Cancer Risk and Prevention Program

Maine Medical Center

Investivator, Center for Outcomes Research and Evaluation

(207) 885-7600 Office

(207) 885-7610 Fax

Dr. Susan Miesfeldt received her Bachelors degree from the University of Vermont, and her MD from Tufts University School of Medicine in 1984, and went on to complete her Internal Medicine residency at the University of Virginia, and her Hematology/Oncology Fellowship training at the University of Michigan School of Medicine, Ann Arbor, where she was a Howard Hughes Fellow. She was an Associate Professor and Director of the Cancer Genetics Clinic at the University of Virginia’s Health Sciences Center, and since 1997, has been a member of the NIH’s Cancer Genetics Studies Consortium. Presently, she serves as the Medical Director for the Cancer Risk and Prevention Program at Maine Medical Center. Dr. Miesfeldt has authored several book chapters and many peer-reviewed articles, in addition to internet and video educational tools.

Selected peer-review publications (in chronological order)

Cooney KA, McCarthy JD, Lange E, Huang L, Miesfeldt S, Montie JE, Lange K. Hereditary prostate cancer criteria identify families linked to prostate cancer susceptibility locus on 1. J Natl Cancer 1997; 89:955-59.
Miesfeldt S, Turner BL, Lovell M, Andersen W, Cooper MR, Jones SM. A novel BRCA1 mutation in an identical twin pair with similar clinical histories. Cancer Genet Cytogenet 1998; 100:43-48.
Cooney KA, Tsou HC, Petty E, Miesfeldt S, Ping XL, Gruener AC, Peacocke M. Absence of germline mutations in the PTEN gene in men with a potential inherited predisposition to prostate cancer. Clinical Cancer Research 1999; 5:1387-1391.
Miesfeldt S, Cohn W, Haden K, Turner B, Fries T, Clark S, Lippert M, Jones S. Men's attitudes about testing for hereditary prostate cancer. Urology 1999; 55:46-50.
Marsh DJ, Kum JB, Lunetta KL, Bennett MJ, Gorlin RJ, Bodurtha J, Corwe C, Dunn T, Graham JM, Hodgson MA, Hudgins L, Hunter A, Jacksonn CE, Koref BR, Manchester D, Miesfeldt S, Murday VA, Nathanson K, Parisim, Poter B, Romano C, Tolmie JL, Trembath R, Winter RM, Zakai E, Zori RT, Dahia LM, Weng L, Eng C. PTEN mutation spectra and genotype-phenotype correlations in Bannayan-Riley-Rnvalcaba syndrome suggest a single entity with Cowden syndrome HMG. Hum Mol Gen 1999;8:1461-72.
Miesfeldt S, Jones S, Cohn W. Informed consent for BRCA 1 and BRCA 2 testing: what clinicians should know about the process and content. JAMA 2000; 55:275-279.
Geer K, Cohn W, Ropka M, Jones S, Miesfeldt S. Attitudes related to patients’ decisions to decline cancer genetics counseling services. J Genetic Counseling 2001; 10:25-40.
Paschold C, Miesfeldt S. Hereditary breast cancer: an update. The Female Patient 2002; 27:15-24.
Miesfeldt S, Jones S, Cohn W, Ropka M. Knowledge about breast cancer risk factors and hereditary breast cancer among women with early-onset breast cancer. Familial Cancer 2002; 1:35-141.
Miesfeldt S, Cohn W, Jones S, Ropka W, Weinstein J. Breast cancer survivors’ attitudes about communication of breast cancer risk to their children. AJMG 2003; 119C:45-50.
Cohn W, Ropka M, Jones S, Fraser G, Miesfeldt S. Information needs about hereditary breast cancer reported by women with early-onset breast cancer. Cancer Det and Prev 2003; 27:345-352.
Lindor L, Peterson G, Hadley D, Kinney A, Miesfeldt S, Lu K, Lynch P, Burke W, Press N. Recommendations for care of individuals with an inherited predisposition to Lynch Syndrome. JAMA 2006; 296:1507-17.
Zbuk K, Patocs A, Shealy A, Sylvester H, Miesfeldt S, Eng C. Germline mutations in PTEN and SDHC in a woman with epithelial thyroid cancer and carotid paraganglioma. Nature Clinical Practice 2007; 4: 608-12
Zbuk K, Patocs A, Shealy A, Sylvester H, Miesfeldt S, Eng C. Germline mutations in both the PTEN tumor suppressor gene and the SDHC mitochondrial complex II gene in a young woman with epithelial thyroid cancer and carotid paraganglioma: implications for cancer risk assessment and management. Nature Clinical Practice Oncology 2007; 4:608-612.
Plumer A, Duan H, Subramaniam S, Lucas FL, Miesfeldt S, Ah-Kua NG, Liaw L. Development of fragment- specific osteopontin antibodies and ELISA for quantification in human metastatic breast cancer. BMC Cancer 2008; 8:38.
Cohn W, Jones S, Miesfeldt S. “Are You at Risk for Hereditary Breast Cancer?” Development of a Personal Risk Assessment Tool for Hereditary Breast and Ovarian Cancer. J Genet Couns 2008; 17:64-78.

Selected Book Chapters

Miesfeldt S, Jameson JL. Screening, prevention, and counseling for genetic disorders. Harrison’s Principles of Internal Medicine 15th ed, McGraw Hill, NY, 2001.
Miesfeldt S, Jameson JL. The practice of genetics in clinical medicine. Harrison’s Principles of Internal Medicine 16th ed, McGraw Hill, NY, 2005.
Miesfeldt S, Jameson JL. The practice of genetics in clinical medicine. Harrison’s Principles of Internal Medicine 17th ed, McGraw Hill, NY, in press.

Internet and Videotape Educational Tools

“Beyond the barriers: effective breast cancer early detection strategies for older women”. Virginia Health Quality Center, Richmond, VA. June 2001.
“Body and soul: addressing cancer risk factors among African American women”. Komen Foundation, University of Virginia, Charlottesville, VA. September 2000.
“The cancer family: a teaching module for primary care clinicians”. Arthur Vining Davis Foundation, University of Virginia, Charlottesville, VA. June 2002.
“Breast cancer: prevention, screening and diagnosis a review for primary care physicians in the United States”. CD-ROM, June 2002.