Daniel Spratt MD

Department of Obstetrics and Gynecology
Division of Reproductive Endocrinology and Infertility
Maine Center for Reproductive Health
778 Main Street, South Portland, ME  04106
(207) 775-1255 Office
(207) 775-1299 Fax
spratd@mmc.org

Biosketch

Dr. Spratt graduated from Stanford University and the University of Michigan Medical School.  After an internship in the U.C. Davis system and an Internal Medicine residency at Santa Clara Valley Medical Center, Dr. Spratt completed a Clinical and Research Fellowship at Massachusetts General Hospital in the Reproductive Endocrine Unit.  Dr. Spratt joined the staff of Maine Medical Center in 1986. He is the Director of the Division of Reproductive Endocrinology and Infertility in the Department of Ob/Gyn at Maine Medical Center, and Professor of Medicine on the part-time faculty of the University of Vermont Medical School.  He heads the Endocrine Research Program at MMCRI, and is incoming chair of MMC’s Clinical Research Advisory Board.  Dr. Spratt is also on the Finance Committee and the AMA delegation of the Endocrine Society. 

Research Interests

Dr. Spratt conducts research protocols in areas of Reproductive Endocrinology and Infertility.  Clinical trials involve therapies for fertility, PCOS, endometriosis, menopause, and osteoporosis.  Dr. Spratt’s group also studies the sex steroid responses to acute illness and stress.

Selected Publications

Spratt DI, Altered Gonadal Steroidogenesis in Critical Illness: Is Treatment with Anabolic Steroids Indicated?, Bailliere’s Best Practices in Endocrinology,15:479-494, 2001

Simmons EM, Himmelfarb J, Sezer MT, Chertow G, Mehta RL, Paganini EP, Soroko S, Freedman S, Becker K, Spratt D, Shyr Y, Ikizler TA, Plasma cytokine levels predict mortality in patients with acute renal failure.  Kidney International, 65:1-9, 2004

Spratt DI, Morton JR, Kramer RS, Mayo SW, Longcope C, and Vary C.P.H., Increases in serum estrogen levels during major illness are caused by increased peripheral aromatization, Am J Physiol Endocrinol Metab 291:E631-8, 2006

Spratt DI, Frohnauer M, Cyr-Alves H, Lucas FL, Kramer RS, Morton JR,  Cox DF, Becker K, Devlin JT.  Physiologic effects of nonthyroidal illness syndrome in patients following cardiac surgery.  In press, Am J Physiol Endocrinol Metab, 2007